Comparison of two different ultrasound techniques for cooled radiofrequency ablation treatment of knee osteoarthritis

Completed

• Conditions: Bilateral primary osteoarthritis of knee, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2022/11/047701
• Lead Sponsor: Lady Hardinge Medical College

Brief Summary

Knee osteoarthritis is one of the most common degenerative conditions in the elderly age group. The definitive treatment is knee replacement surgery, but most of the patients will not be fit for surgery. Minimally invasive procedures like radiofrequency ablation of genicular nerves around the knee joint is a successful alternative for surgery. Cooled Radiofrequency ablation is a new modality that effectively ablates the genicular nerves. Previously it was done under fluoroscopy guidance but ultrasound guidance has better advantages of being radiation free and accurate capturing of nerves. Previous landmarks that have been used for ultrasound guided ablation did not cover the entire nerves, thus providing less pain relief. Recently developed revised anatomical landmarks effectively block the genicular nerves and provide better pain relief than conventional technique.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-30
• Study Completion: 2024-01-02
• Last Update Posted: 2025-04-18

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Patients with symptomatic knee osteoarthritis graded II,III&IV according to the Kellgren-Lawrence system.

Exclusion Criteria

• Pain and functional limitations due to rheumatoid arthritis, gout and psoriatic arthritis.
• Active infection of knee joint 3.
• Patients receiving any other invasive treatment for knee osteoarthritis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in the median Oxford Knee Score	after 1, 4 and 12 weeks

Secondary Outcome Measures

Name	Time	Method
Median Numerical Rating Scale (NRS)	after 1, 4 and 12 weeks
Proportion of patients developing skin burns, hematoma and numbness	immediately and within 1 week

Trial Locations

Locations (1)

Lady Hardinge Medical College; 🇮🇳 Delhi, DELHI, India

Lady Hardinge Medical College

🇮🇳Delhi, DELHI, India

Dr Divya V

Principal investigator

08838966863

divyavelu777@gmail.com