Reducing and interrupting prolonged sitting time in adults with pre-diabetes: A pilot study of feasibility and acceptability of a real-life interventio

Not Applicable

• Conditions: pre-diabetes; Public Health - Health promotion/education; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12615001092583
• Lead Sponsor: Baker IDI Heart and Diabetes Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-19
• Study Completion: 2016-08-26
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

From the general community, overweight or obese adults aged between 45-65 years, with diagnosed pre-diabetes (within the last 6 months), impaired fasting glucose and/or impaired glucose tolerance according to current World Health Organisation diagnostic criteria, who are working at least 0.5 full-time equivalent and able to elicit employer permission to install the provided sit-stand workstation.

Exclusion Criteria

Previously diagnosed diabetes and/or use of glucose altering medications, regularly engaged in moderate-vigorous exercise (>150 min/week for > 3 months), self reported to be sitting <9 hours per day, pregnant, current smoker, and known physical activity contraindications and/or medical illness that may limit their ability to participate in the intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postprandial plasma glucose levels: (mean area under the curve [AUC]). Plasma glucose concentrations will be assessed during a 3 hour 75 g Oral Glucose Tolerance Test[Blood samples for glucose analysis will be collected every 1/2 hour for 3 hours - both at baseline and after the 4 week intervention is completed.];Postprandial plasma insulin levels: (mean area under the curve [AUC]). Plasma insulin concentrations will be assessed during a 3 hour 75 g Oral Glucose Tolerance Test[Blood samples for insulin analysis will be collected every 1/2 hour for 3 hours - both at baseline and after the 4 week intervention is completed.]