KCT0003573
Recruiting
未知
Product to predict the progression of diabetic nephropathy using urinary exosomal microRNA
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Gachon University Gil Medical Center
- Enrollment
- 270
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Type 2 diabetic patients diagnosed at the age of 30 or older
- •\- Aged 75 and younger
- •\- Patients with eGFR and albuminuria recordings at least three times in intervals of at least 3 months
- •\- Patients taking antihypertensive agents and angiotensin converting enzyme (ACE) inhibitor / angiotensin II receptor blocker (ARB) for hypertension or albuminuria have been receiving stable doses for more than 2 weeks
- •As a healthy healthy control group, adult subjects who aged more than 30 and 75 or less years old, with neither diabetes nor chronic kidney disease
Exclusion Criteria
- •? Under the age of 30 or over 75 years old
- •? Patients with type 1 diabetes or diabetic ketoacidosis
- •? Patients with CKD unrelated to diabetes
- •? Patients with poor blood pressure control or those taking 4 or more classes of antihypertensive drugs
- •? Patients with kidney transplantation or single kidney, patients with genetic kidney disease
- •? Among retrospective trajectory data, initial urine albumin/creation ratio (UACR)\> 3500 mg/g, hemoglobin \<11 g/dL, or serum albumin \<3\.6 g/dL
- •? Hemoglobin A1c level\> 11\.0% at enrollment,
- •? A history of dialysis or a history of acute kidney injury
- •? Other severe systemic disease or BMI \<18\.5 kg /square meters
- •? Pregnant women
Outcomes
Primary Outcomes
Not specified
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