Eradication of Helicobacter pylori infection by sequential regimen and standard quadruple

Phase 1

• Conditions: Helicobacter pylori.; Helicobacter pylori [H.pylori] as the cause of diseases; B98.0

• Registration Number: IRCT20191007045022N1
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Patients with functional dyspepsia or gastroduodenal ulcer with indication of eradication of Helicobacter pylori infection
Ability and willingness to participate in study and to give informed consent
Verification of Helicobacter pylori infection by endoscopic pathological specimen

Exclusion Criteria

Previous eradication of Helicobacter pylori
Use of antibiotics, PPI or chemotherapy during 4 weeks prior to study
Patients with a history of gastrectomy or Complicated Peptic Ulcer.
Pregnant and lactating women
Patients with renal failure and heart failure

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fecal antigen reduction. Timepoint: Helicobacter pylori eradication was assessed at least 2 months after the end of antibiotic treatment and at least 2 weeks after omeprazole discontinuation via fecal antigen. Method of measurement: Fecal testing.