Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Completed

• Conditions: Chronic Lung Allograft Dysfunction (CLAD)

• Registration Number: NCT02836938
• Lead Sponsor: Prof. Dr. Jens Hohlfeld

Brief Summary

It's the aim of this study to clarify, whether the non-invasive assessment of breath can serve as a novel clinical tool to assist in the diagnosis of CLAD. If different stages of BOS can be discriminated by the level of certain VOCs than there would also be a potential to actually predict the development at an early stage and would enable an earlier intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06
• Study First Submitted: 2016-07-05
• Study First Submitted QC: 2016-07-14
• Study First Posted: 2016-07-19
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-13
• Last Update Posted: 2017-02-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Outpatient bilateral lung transplant recipients including combined transplants

Exclusion Criteria

• Active Smoking Oxygen therapy Infection with multi or pan-resistant bacteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentration of exhaled breath volatile organic compounds	one sample will be collected between 6 month and 20 years after lung transplantation

Trial Locations

Locations (1)

Hannover Medical School; 🇩🇪 Hannover, Germany