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Clinical Trials/NCT02836938
NCT02836938
Completed
Not Applicable

Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Prof. Dr. Jens Hohlfeld1 site in 1 country75 target enrollmentJune 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Lung Allograft Dysfunction (CLAD)
Sponsor
Prof. Dr. Jens Hohlfeld
Enrollment
75
Locations
1
Primary Endpoint
Concentration of exhaled breath volatile organic compounds
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

It's the aim of this study to clarify, whether the non-invasive assessment of breath can serve as a novel clinical tool to assist in the diagnosis of CLAD. If different stages of BOS can be discriminated by the level of certain VOCs than there would also be a potential to actually predict the development at an early stage and would enable an earlier intervention.

Registry
clinicaltrials.gov
Start Date
June 2016
End Date
December 2016
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Prof. Dr. Jens Hohlfeld
Responsible Party
Sponsor Investigator
Principal Investigator

Prof. Dr. Jens Hohlfeld

Prof. Dr.

Fraunhofer-Institute of Toxicology and Experimental Medicine

Eligibility Criteria

Inclusion Criteria

  • Outpatient bilateral lung transplant recipients including combined transplants

Exclusion Criteria

  • Active Smoking Oxygen therapy Infection with multi or pan-resistant bacteria

Outcomes

Primary Outcomes

Concentration of exhaled breath volatile organic compounds

Time Frame: one sample will be collected between 6 month and 20 years after lung transplantation

Study Sites (1)

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