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临床试验/NCT02836938
NCT02836938已完成不适用

Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Prof. Dr. Jens Hohlfeld1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2016年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
75
试验地点
1
主要终点
Concentration of exhaled breath volatile organic compounds

研究概览

简要总结

It's the aim of this study to clarify, whether the non-invasive assessment of breath can serve as a novel clinical tool to assist in the diagnosis of CLAD. If different stages of BOS can be discriminated by the level of certain VOCs than there would also be a potential to actually predict the development at an early stage and would enable an earlier intervention.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Outpatient bilateral lung transplant recipients including combined transplants

排除标准

  • Active Smoking Oxygen therapy Infection with multi or pan-resistant bacteria

结局指标

主要结局

Concentration of exhaled breath volatile organic compounds

时间窗: one sample will be collected between 6 month and 20 years after lung transplantation

次要结局

未报告次要终点

研究者

发起方
Prof. Dr. Jens Hohlfeld
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Prof. Dr. Jens Hohlfeld

Prof. Dr.

Fraunhofer-Institute of Toxicology and Experimental Medicine

研究点 (1)

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