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Outcomes of FIrst and possibility of REdo-TAVI with different transcatheter heart valves

Recruiting
Conditions
aortic stenosis
Registration Number
DRKS00031563
Lead Sponsor
Deutsches Herzzentrum der Charité
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
260
Inclusion Criteria

Patients with aortic regurgitation or stenosis and performed TAVI (01.01.2018-30.09.2022)

Exclusion Criteria

None

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Combined safety endpoint of all-cause mortality, myocardial infarction, stroke, life-threatening bleeding requiring transfusion, acute kidney injury with need for dialysis, and relevant vascular complications (defined according to the VARC 3 criteria) at discharge from the index hospitalization.
Secondary Outcome Measures
NameTimeMethod
Procedural outcome (up to discharge from index hospitalization):<br>Cardiovascular mortality<br>Echocardiography post-TAVI: moderate to severe aortic regurgitation, mean preassure gradient<br>Need of a new pacemaker<br>Complications according to Valve Academic Research Consortium (VARC) 3 criteria <br>Neo skirt height as a risk factor for coronary obstruction in case of redo-TAVI<br>Follow-up with regard to survival, hospitalisations and symptoms
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