Survival of autologous fat transfer (AFT) for scar remodeling with and without platelet rich plasma (PRP)

Not Applicable

• Conditions: scar; Skin - Other skin conditions; skin graft; Blood - Normal development and function of platelets and erythrocytes; Surgery - Surgical techniques

• Registration Number: ACTRN12618001886279
• Lead Sponsor: Dr. Hassan Saeed Khan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-20
• Last Update Posted: 26 November 2018

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

At least 2 separate (i.e. non-contiguous) or 1 large wound/scar previously healed by placement of a STSG and/or by secondary intention (study sites), each Less than or equal to 80 cm2 in size (area).The sites should be similar in size and anatomical location (e.g. upper arms; trunk; legs) to the extent practically possible.
Adequate adipose available for harvesting

Exclusion Criteria

1.Life or limb-threatening injury/disease determined on history and clinical examination.
2.Active drug use/abuse determined on history
3.Pregnancy confirmed on urine test.
4.History of bleeding tendency/inability to clot,determined on PT, APTT and/or INR more than or equal to 2.2.
5.Smoking will be assessed on history

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assess the outcome of survival of autologous fat transfer (AFT)) with/without PRP in terms of fat grafting or fat transfer, fat survival.[Fat survival will be assessed by pre and 3 months post treatment Ultrasound measurement of the depth of subcutaneous tissue]

Secondary Outcome Measures

Name	Time	Method
Assess the outcome of survival of autologous fat transfer (AFT)) with/without PRP in terms of scar remodeling.[Will be assessed by Visual analogue scale at pre and 3 months post treatment.]