Evaluation of the spontaneous breathing test in predicting the withdrawal from mechanical ventilation after cardiac surgery in childre

Not Applicable

• Conditions: Q24.9; artificial respiration; congenital malformation of the heart; E02.041.625

• Registration Number: RBR-62h256
• Lead Sponsor: Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Children; aged 0-18 years; with congenital heart disease; admitted to the pediatric intensive care unit after cardiac surgery; receiving mechanical ventilation for more than 12 hours.

Exclusion Criteria

preoperative mechanical ventilation; uncontrolled pulmonary hypertension; refusal to participate.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Extubation success defined as no need for reintubation within 48 hours after extubation. ;Extubation success was more frequent in patients in the spontaneous breathing trial group compared with the control group (83% vs. 68%, p = 0.02).

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes were PICU length of stay, hospital length of stay, incidence of ventilator-associated pneumonia defined by the 2007 CDC criteria, mortality.;Patients in the spontaneous breathing trial group had a shorter PICU length of stay (hazard ratio 2.96; 95% CI 2-4.28, p<0.01). Duration of mechanical ventilation,hospital length of stay, incidence of ventilator associated pneumonia and mortality were not significantly different in both groups.