Reducing sarcopenia and maintaining independent living in frail older adults via reductions in sitting time: the Frail-LESS (LEss Sitting and Sarcopenia in Frail older adults) intervention

Brunel University London0 个研究点目标入组 60 人开始时间: 2021年8月6日最近更新: 2024年4月8日

适应症

试验速览

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36609363/ (added 09/01/2023)

•1. Community-dwelling older adults aged =65 years
•2. Mild frailty classified according to the Clinical Frailty Scale. This describes people who have more evident slowing, and need help in high order instrumental activities of daily living (finances, transportation, heavy housework, medications). Typically, mild frailty progressively impairs shopping and walking outside alone, meal preparation and housework
•3. Spend the majority of the day (>60%) sitting. This will be initially measured by self-report using the International Physical Activity Questionnaire item on daily sitting (During the last 7 days, how much time did you spend sitting on a week day?”). This will be confirmed with a device-based measure during baseline data collection
•4. Functional Ambulation Category rating of =4 i.e. able to ambulate independently with or without a walking aid on level surfaces without supervision or assistance from another person

•1. Unable to ambulate independently
•2. Unable to communicate in English in order to meet the requirements of the study procedures
•3. Any unstable medical conditions
•4. Cognitive impairment (score =7 in the 6 Item Cognitive Impairment Test). This test will be administered over the phone by a researcher
•5. Fitted with a pacemaker as this would preclude participants from completing the muscle mass measurements

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