NCT00390936已完成1 期
Phase I Multiple Ascending Dose Study to Determine the Safety, Pharmacokinetics and Pharmacodynamics of BMS-582664 in Japanese Patients With Advanced or Metastatic Solid Tumors
Bristol-Myers Squibb1 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2007年10月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- Dose Limiting Toxicity
研究概览
简要总结
The purpose of this study is to assess the dose limiting toxicity (DLT) of BMS-582664 and the maximum tolerated dose(MTD) in subjects with advanced or metastatic solid tumors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have measurable disease
- •Documented failure to standard therapies exist, or which are determined to be inappropriate by the investigator
- •ECOG PS: 0-1
排除标准
- •Subjects with centrally located squamous cell carcinoma of the lung
研究组 & 干预措施
1
No Intervention
4 dosages
干预措施: Brivanib (Drug)
结局指标
主要结局
Dose Limiting Toxicity
时间窗: at the end of the first cycle of the study
Maximum Tolerated Dose
时间窗: at the end of the first cycle of the study
次要结局
- To assess any preliminary evidence of anti-tumor activity observed with BMS-582664(at the end of the study)
研究者
研究点 (1)
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