Molecular Mediators of Nerve Injury Signaling

• Conditions: Diabetes; Nerve Injury; Chronic Neuropathic Pain

• Registration Number: NCT01437332
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states such as diabetes. In this study, the investigators hypothesize that it is possible to detect changes in specific signaling molecules and that these will provide insights into novel treatment strategies. The patients to be included are those who are undergoing the removal of tissue during surgery. The tissues that would otherwise be discarded will be included in the study as appropriate.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-09
• Study Start: 2011-09
• Study First Submitted: 2011-09-19
• Study First Submitted QC: 2011-09-19
• Last Update Submitted: 2011-09-19
• Study First Posted: 2011-09-20
• Last Update Posted: 2011-09-20
• Primary Completion: 2016-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients undergoing surgery where tissue removal is anticipated

Exclusion Criteria

• age younger than 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Rambam Health Care Campus; 🇮🇱 Haifa, Israel