A Large-scale, Prospective Screening Programme for Malignant Tumors Using Routine Blood Tests Parameters
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hematologic Tests
- Sponsor
- Sun Yat-sen University
- Enrollment
- 10000
- Locations
- 1
- Primary Endpoint
- sensitivity (true positive rate)
- Last Updated
- 6 years ago
Overview
Brief Summary
In prospective part of study, the investigators have found that the parameters of routine blood tests can differentiate varieties of malignancy from healthy people.
The investigators enrolled healthy subjects and patients with malignancy that aged from 18 to 85，and collected their clinical data and blood tests result to build the model.And retrospectlly enroll healthy subjects and patients to test the model.
Investigators
Ruihua Xu
President
Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •Asymptomatic persons between the ages of 18 to 80 years
- •Chinese ethnicity
- •After 3 year follow-up, diagnosed with no malignant disease
- •Subject underwent routine blood tests in our center
Exclusion Criteria
- •1.With a history of malignant disease
- •For the cohort of patients with malignancy
- •Inclusion Criteria:
- •diagnosis with the following malignant disease，breast cancer, lung cancer, gastric cancer， esophageal cancer，colorectal cancer，nasopharyngeal cancer，liver cancer and cervical cancer
- •Subject underwent routine blood tests in our center
Outcomes
Primary Outcomes
sensitivity (true positive rate)
Time Frame: 1 year
The proportion of persons with disease who have a positive test (positive test results among persons with disease)
Specificity (true negative rate)
Time Frame: 1 year
The proportion of persons without disease who have a negative test (negative test results among persons without disease)