Comparison of hand sensibility and nerve conduction in individuals with and without neurodynamic response of upper limb
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 134
- Locations
- 1
- Primary Endpoint
- Elbow extension angle in degrees in Upper limb neurodynamic test (ULNT 1) , Hand Sensibility Measures includes Vibration Threshold in Volts,
Study Overview
Brief Summary
An altered upper limb neurodynamic testing (ULNT 1) and abnormal nerve conduction serve as early indicators of peripheral neural dysfunctions that may aid in detecting unknown subclinical pathology in healthy adult individual. Also altered sensibility may also suggest change in sensory nerve fibers but there is dearth in study comparing the sensory nerve conduction velocity in individuals with and without altered neurodynamic tension. Therefore study aims to compare hand sensibility measures, including Vibration Threshold, Two-point Discrimination, Monofilament testing, and nerve conduction, in asymptomatic individuals with altered responses to upper limb neurodynamic testing.The study begins with the screening of asymptomatic healthy individuals approached through advertisement flyers distributed at various locations. Written informed consent will be obtained from participants before performing ULNT, after which participants will be categorized into the study or comparison group based on the response to ULNT . Subsequently, hand sensibility measures such as vibration threshold using a bioesthesiometer, two-point discrimination using a Disk-criminator, light touch using monofilament testing, and nerve conduction amplitude and velocity using a Sensory nerve conduction machine will be measured.
The study will continue until January 2025. Data obtained will be analyzed using Jamovi 2.3.28.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 20.00 Year(s) to 45.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Study Group: Participants presenting responses like pain, tingling, and numbness before 30 degrees of end-range elbow extension while performing upper limb neurodynamic test -1 (ULNT-1) sequence.
- •Comparison Group: Participants without any response or response at terminal range of elbow extension while performing ULNT-1 sequence.
Exclusion Criteria
- •Previous history of upper limb / cervical neural symptoms of pain or dysfunction for last 3 months.
- •Known case of diabetes, thoracic outlet syndrome, brachial plexus injury, spinal cord injury, spinal disorders, cancer, tumors.
Outcomes
Primary Outcomes
Elbow extension angle in degrees in Upper limb neurodynamic test (ULNT 1) , Hand Sensibility Measures includes Vibration Threshold in Volts,
Time Frame: Baseline
Two Point Discrimination Score 0- 10, Monofilament Testing Score 0-21 and velocity (m/s ), Amplitude (m/s) in Sensory nerve conduction study
Time Frame: Baseline
Secondary Outcomes
- Not Applicable(Not Applicable)
Investigators
Harshika Raut
Manipal College of Health Professions, Manipal Academy of Higher Education