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A study to compare different Prakriti prediction methods

Completed
Conditions
healthy adults
Registration Number
CTRI/2022/04/041747
Lead Sponsor
Center for Integrative Medicine and Research
Brief Summary

In the Ayurvedic system of medicine, prevention and therapeutic measures are based on understanding and assessing the individual constitution, or *Prakriti*, of patients for choosing the most appropriate regimen, drugs, and lifestyle measures. So, standardization of the *Prakriti* assessment technique is essential for applying the personalized approach and getting the maximum benefit of Ayurvedic diagnostic, therapeutic, and prophylactic measures. Among the majorly used *Prakriti* questionnaires, the CSIR-TRISUTRA   consortium initiative is an integrative approach involving the identification of molecular correlates of *Prakriti* as predictive and prognostic markers of disease as well as therapeutic response. A comprehensive       *Prakriti*assessment model has been developed by CCRAS (Central      Council for Research in Ayurvedic Sciences) and is being used for testing healthy volunteers. C-DAC is also utilized by several research studies for prognosis, evaluating therapeutic efficacy, and finding associations of phenotypes and genotypes.

Though all the questionnaires are derived from the Ayurvedic classical texts they vary in their construct and approach. Scare data is available regarding their standardization and validation procedures. There are no studies available, evaluating the agreement between different questionnaires and their comparison with physician’s *Prakriti* assessment. Though the *Prakriti* assessment questionnaires are based on Ayurvedic classical texts, they differ in their derivation, structure, and algorithms for scoring and assignment of the *Prakriti.* Therefore, there is a need to evaluate the agreement in Prakriti prediction by Ayurveda physicians as a reference to the Questionnaire-based *Prakriti* assignment.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
197
Inclusion Criteria
  • Subjects willing to participate in the study, who give informed written consent and are able to comply with the study visit requirements 2.
  • Able to understand Hindi and English language properly for comprehending the Prakriti assessment.
Exclusion Criteria
  • Individuals with diagnosed major disease conditions (self-reported) such as advanced malignancies, significant systemic diseases like chronic kidney diseases, severe hepatic, pulmonary, cardiac disease, and other neurologic diseases 2.
  • Individuals diagnosed clinically with major psychiatric disorder (e.g., psychosis, major depression, bipolar disorder), that can interfere with Prakriti assessment 3.
  • Unable to comply with the study requirements.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Sensitivity and Specificity of two questionnaires based approaches for ten Prakriti types by considering the prakriti assignment by Ayurvedic physician as gold standard.data will be recorded only once (cross sectional study)
Secondary Outcome Measures
NameTimeMethod
Agreement between CSIR Prakriti questionnaire and CCRAS Prakriti questionnaire with a reference of Ayurvedic clinicians assessment.data will be recorded only once (cross sectional study)

Trial Locations

Locations (1)

Center for Integrative Medicine and Research

🇮🇳

South, DELHI, India

Center for Integrative Medicine and Research
🇮🇳South, DELHI, India
Dr Gautam Sharma
Principal investigator
011-26549320
drgautamsharma12@gmail.com

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