Effects of a Program of Deep Inspiration Combined to Expiratory Positive Airway in Quality of Life and Heart Rate Variability
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- The effect of deep inspiration and positive expiratory airway pressure in quality of life in adults with severe asthma
Study Overview
Brief Summary
The purpose of this study is to determine the effects of a deep inspiration combined to expiratory positive airway pressure protocol on respiratory function, quality of life, exercise tolerance and heart rate variability in adults with severe asthma.
Detailed Description
Asthma is associated with high morbidity and significant mortality. This disease has functional impact on activities of daily living (ADLs) and according to some studies in the United States and Europe, the percentage of asthmatics who have significant restrictions in their ADLs is quite significant. Asthma is characterized as a major public health problem, not only in Brazil but worldwide. Currently there are few studies reporting the effects of a domiciliary program of deep inspiration associated with positive expiratory pressure in the airways of asthmatics. This study aims to analyze the benefits of this program on lung function, quality of life and response to exercise.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 20 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age between 20 and 80
- •Severe asthma
Exclusion Criteria
- •Disagreement with consent form
- •Other respiratory disease
- •Acute severe asthma
- •Pregnancy or breastfeeding
- •Current smoking
- •Lack of capable of conducting the study visits
Arms & Interventions
Deep inspiration and expiratory positive airway pressure
The protocol of deep inspiration combined to expiratory positive airway pressure will be applied in asthmatic subjects.
Intervention: Deep inspiration and positive expiratory airway pressure (Other)
Control
Outcomes
Primary Outcomes
The effect of deep inspiration and positive expiratory airway pressure in quality of life in adults with severe asthma
Time Frame: Change in quality of life at 5 week
The quality of life will be measure by a specific questionnaire for this population 5 weeks apart.
Secondary Outcomes
- The effect of deep inspiration and positive expiratory airway pressure in respiratory function in adults with severe asthma.(Change in respiratory function at 5 week)
- The effect of deep inspiration and positive expiratory airway pressure in exercise tolerance in adults with severe asthma.(Change in exercise tolerance at 5 week)
- The effect of deep inspiration and positive expiratory airway pressure in heart rate variability in adults with severe asthma.(Change in heart rate variability at 5 week)
Investigators
Pedro Dal Lago
Professor
Federal University of Health Science of Porto Alegre