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Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar

Not Applicable
Completed
Conditions
Acne Scar
Interventions
Procedure: fractional carbon dioxide laser with NS
Procedure: fractional carbon dioxide laser with platelet rich plasma
Registration Number
NCT02396290
Lead Sponsor
Seoul National University Hospital
Brief Summary

Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar

Detailed Description

Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
29
Inclusion Criteria
  • moderate to severe acne scar
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Exclusion Criteria
  • taken procedures for acne scar within 6 months
  • underlying diabetes mellitus, keloid, or malignancy
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
fractional CO2 laser with NSfractional carbon dioxide laser with NSfractional carbon dioxide laser followed by intradermal injection of NS
fractional CO2 laser with PRPfractional carbon dioxide laser with platelet rich plasmafractional carbon dioxide laser followed by intradermal injection of platelet rich plasma
Primary Outcome Measures
NameTimeMethod
Global assessment of acne scar12 weeks

5-point grading of acne scar

Secondary Outcome Measures
NameTimeMethod
adverse effect assessment12 weeks

adverse effect assessment - erythema index, Epithelization Scale (0-12 point)

ECCA (échelle d'évaluation clinique des cicatrices d'acné)12 weeks

quantitative analysis of acne scar

Trial Locations

Locations (1)

Department of Dermatology, Seoul National University College of Medicine

🇰🇷

Seoul, Korea, Republic of

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