Therapeutic Effect of Mulberry Fruit Powder Consumption in Metabolic Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Lipid profile will be assessed before and after the trial.
研究概览
简要总结
Metabolic syndrome is a raising concern globally, especially in developing countries such as Pakistan. To prevent its risk factors diet and lifestyle modification is major solution. Functional foods have additional benefits of treating disease while providing basic nutrients. Mulberry is a native fruit with the properties of functional food, it is rich in anthocyanin and different anti-obesity,anti-diabetic, and anti-hyperlipidemic treating potential antioxidants. Mulberry will prove its therapeutic potential against the risk factors of metabolic syndrome.
详细描述
Metabolic syndrome, which is characterized by a number of concurrent risk factors. These risk factors include dysglycemia, high blood pressure, high triglyceride levels, low levels of HDL cholesterol, and obesity (particularly central adiposity). It is rapidly increasing the burden of non-communicable diseases (NCDs) in Pakistan. The prevalence of MetS in Pakistan is 28.6%, and suburban areas from the province of Punjab showed a high prevalence. Females are more prone to metabolic syndrome. Dietary and lifestyle modification can prevent MetS from converting into CVD, T2DM, and stroke. There is limited documented research in Pakistan related to the therapeutic roles of mulberry fruit powder. With respect to these limitations, the present study aims to assess the therapeutic roles of mulberry fruit powder consumption on metabolic syndrome.
The utilization of dried mulberry fruit powder (MFP) as a component of nutritional supplementation will effectively ameliorate the clinical markers associated with metabolic syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
盲法说明
Participants groups
入排标准
- 年龄范围
- 35 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects having fasting total cholesterol level of ≥ 200 mg/dl or LDL cholesterol ≥ 130 mg/dl.
- •Fasting Blood Glucose ≥110mg/dl.
- •SBP ≥ 130/ ≥ 85 mmHg
- •Waist Circumference of ≥40 inches in males and ≥35 inches for females
排除标准
- •Participants of age 55 or above
- •Participants who have less than two risk factors
结局指标
主要结局
Lipid profile will be assessed before and after the trial.
时间窗: 45 days
The change in lipid profile, after consuming mulberry fruit powder for 45 days, will be assessed. The value will be closed to optimized values.
Fasting glucose level will be assessed before and after the trial
时间窗: 45 days
The change in fasting glucose levels will be assessed after consuming mulberry fruit powder for 45 days.The values will be become close to optimized levels
Weight circumference will be measured before and after the trial
时间窗: 45 days
The change in weight will be measured after consuming mulberry fruit powder for 45 days.The value will be close to normal range.
Blood pressure will be assessed before and after the trial.
时间窗: 45 days
The change in systolic and diastolic blood pressure, after consuming mulberry fruit powder for 45 days. The values will become close to optimized levels.
次要结局
未报告次要终点
研究者
Asif Ali
Lecturer, Department of Food Sciences and Human Nutrition
University of Veterinary and Animal Sciences, Lahore - Pakistan