MedPath

Effect of Mulberry Fruit Powder in Metabolic Syndrome

Not Applicable
Recruiting
Conditions
Metabolic Syndrome
Interventions
Dietary Supplement: Black Mulberry Fruit Powder
Registration Number
NCT05956106
Lead Sponsor
University of Veterinary and Animal Sciences, Lahore - Pakistan
Brief Summary

Metabolic syndrome is a raising concern globally, especially in developing countries such as Pakistan. To prevent its risk factors diet and lifestyle modification is major solution. Functional foods have additional benefits of treating disease while providing basic nutrients. Mulberry is a native fruit with the properties of functional food, it is rich in anthocyanin and different anti-obesity,anti-diabetic, and anti-hyperlipidemic treating potential antioxidants. Mulberry will prove its therapeutic potential against the risk factors of metabolic syndrome.

Detailed Description

Metabolic syndrome, which is characterized by a number of concurrent risk factors. These risk factors include dysglycemia, high blood pressure, high triglyceride levels, low levels of HDL cholesterol, and obesity (particularly central adiposity). It is rapidly increasing the burden of non-communicable diseases (NCDs) in Pakistan. The prevalence of MetS in Pakistan is 28.6%, and suburban areas from the province of Punjab showed a high prevalence. Females are more prone to metabolic syndrome. Dietary and lifestyle modification can prevent MetS from converting into CVD, T2DM, and stroke. There is limited documented research in Pakistan related to the therapeutic roles of mulberry fruit powder. With respect to these limitations, the present study aims to assess the therapeutic roles of mulberry fruit powder consumption on metabolic syndrome.

The utilization of dried mulberry fruit powder (MFP) as a component of nutritional supplementation will effectively ameliorate the clinical markers associated with metabolic syndrome.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Subjects having fasting total cholesterol level of ≥ 200 mg/dl or LDL cholesterol ≥ 130 mg/dl.
  • Fasting Blood Glucose ≥110mg/dl.
  • SBP ≥ 130/ ≥ 85 mmHg
  • Waist Circumference of ≥40 inches in males and ≥35 inches for females
Exclusion Criteria
  • Participants of age 55 or above
  • Participants who have less than two risk factors

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Metabolic syndrome patientsBlack Mulberry Fruit PowderDried Mulberry fruit powder is used for preventing symptoms in Metabolic Syndrome patients Dietary intervention: Black Mulberry fruit powder Dosage: 45g per day
Primary Outcome Measures
NameTimeMethod
Lipid profile will be assessed before and after the trial.45 days

The change in lipid profile, after consuming mulberry fruit powder for 45 days, will be assessed. The value will be closed to optimized values.

Fasting glucose level will be assessed before and after the trial45 days

The change in fasting glucose levels will be assessed after consuming mulberry fruit powder for 45 days.The values will be become close to optimized levels

Weight circumference will be measured before and after the trial45 days

The change in weight will be measured after consuming mulberry fruit powder for 45 days.The value will be close to normal range.

Blood pressure will be assessed before and after the trial.45 days

The change in systolic and diastolic blood pressure, after consuming mulberry fruit powder for 45 days. The values will become close to optimized levels.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Shan Medicare Hospital

🇵🇰

Arifwala, Punjab, Pakistan

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