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临床试验/NCT07737015
NCT07737015已完成不适用

Effects of a Short Bout of Respiratory Muscle Training on Tongue Corticomotor Excitability in Healthy Adults: A Pilot Study

Université Catholique de Louvain1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2024年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Motor-evoked potentials

研究概览

简要总结

The tongue plays a central role in essential oral functions, including swallowing, speech, and upper airway control. Its coordinated interaction with the respiratory system is particularly relevant in clinical conditions such as obstructive sleep apnea and dysphagia. While respiratory muscle training is increasingly used in these contexts, its effects on the neural control of tongue function remain poorly understood.

This randomized cross-over pilot study aimed to investigate the acute effects of inspiratory (IMT) and expiratory (EMT) muscle training on tongue corticomotor excitability using transcranial magnetic stimulation. These results will provide novel insight into the neurophysiological mechanisms linking respiratory interventions and oral motor control.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18 years of age or older
  • good general health
  • ability to read and understand the project information

排除标准

  • medical, physical or psychological disorder
  • metal implants in the head
  • medications affecting the nervous system
  • craniofacial abnormalities
  • neuromuscular or inflammatory diseases
  • history of epilepsy
  • presence of pacemaker or implanted medical devices
  • pregnancy

结局指标

主要结局

Motor-evoked potentials

时间窗: Measured two times: immediately before the training session (baseline) and immediately after completion of the training session (approximately 45 minutes after baseline)

The amplitude of tongue-related motor-evoked potentials are assessed using transcranial magnetic stimulation over the tongue motor cortex.

次要结局

  • Maximum Inspiratory and Expiratory Pressure(Measured two times: immediately before the training session (baseline) and immediately after completion of the training session (approximately 45 minutes after baseline))
  • Tongue elevation peak pressure(Measured two times: immediately before the training session (baseline) and immediately after completion of the training session (approximately 45 minutes after baseline))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

William Poncin

Principal Investigator, Professor

Université Catholique de Louvain

研究点 (1)

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