A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Cairo University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
Study Overview
Brief Summary
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
Detailed Description
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All age group.
- •Both genders.
- •Subjects with stable non-segmental vitiligo (≥2 patches) acral or non-acral patches of diameter ≤ 2cm.
Exclusion Criteria
- •Prior treatment with laser therapies for at least 3 months
- •Recent exfoliation procedures.
- •Recent surgical procedures.
- •Poor skin conditions including keloids.
- •Hypersensitivity to light ( visible and near-infrared).
- •Medications that make users more sensitive to light.
- •Anticoagulant and immunosuppressive treatments.
- •Gestations or breastfeeding.
- •A personal or family history of skin cancer.
- •Unstable vitiligo (older lesions have not progressed for the last 1 years and lack of Koebner phenomena ).
Arms & Interventions
patients will receive NB-UVB phototherapy sessions on a Randomly selected patch
patients will receive NB-UVB phototherapy sessions on a Randomly selected patch
Intervention: Narrow Band UVB Treatment (Device)
Patients will receive blue light emitting diodes phototherapy on a randomly selected patch
Patients will receive blue light emitting diodes phototherapy on a randomly selected patch
Intervention: blue light emitting diode (Device)
Outcomes
Primary Outcomes
Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
Time Frame: 48 weeks
Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
Secondary Outcomes
No secondary outcomes reported
Investigators
Nahla Maher Mahmoud Mahran
Lecturer of Dermatology
Cairo University