Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Rheumatism Knee
• Interventions: Procedure: single-shot adductor canal block

• Registration Number: NCT04986878
• Lead Sponsor: Aswan University Hospital

Brief Summary

Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).

Detailed Description

Various approaches to the performance of peripheral nerve blocks for postoperative pain control in patients undergoing TKA have been described in the literature. These approaches include lumbar plexus block, femoral nerve block (FNB), with or without a sciatic nerve block, and most recently the ACB. FNB is a commonly used modality for postoperative analgesia after TKA. It is considered by some as the gold standard or the cornerstone of postoperative analgesia after TKA. However, FNB reduces quadriceps muscle strength essential for mobilization and active contribution in any physical rehabilitation program. Quadriceps weakness places the patients at risk of falling. which may be detrimental to postoperative recovery. The ACB has recently emerged as an appealing alternative to FNB as it is predominately a sensory nerve block of a more distal branch of the femoral nerve ( the saphenous nerve).

Study Timeline

• Study Start: 2017-03-15
• Primary Completion: 2018-03-31
• Study Completion: 2018-06-30
• Study First Submitted: 2021-06-30
• Study First Submitted QC: 2021-07-23
• Status Verified: 2021-08
• Study First Posted: 2021-08-03
• Last Update Submitted: 2021-08-03
• Last Update Posted: 2021-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients scheduled for primary total knee arthroplasty with
• American Society of Anesthesiologists (ASA) physical status I -III,
• mentally competent and able to give consent for enrollment in the study.

Exclusion Criteria

1. Patient younger than 18 years old or older than 70 years old
2. Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol.
3. Revision surgeries were excluded.
4. Impaired kidney functions and patients with coagulopathy were also excluded.
5. Chronic pain syndromes and patients with chronic opioid use defined as the use of regular daily doses of systemic narcotics for the past 6 months prior to the surgery.
6. BMI of 40 or more
7. Pregnancy (positive urine pregnancy test result in Preop area on the morning of surgery)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Single shot adductor canal block	single-shot adductor canal block	Following sterile preparation and draping, an ultrasound survey of the medial thigh was performed, halfway between the superior anterior iliac spine and the patella. The superficial femoral artery has been identified beneath the sartorius muscle in a short-axis view, with the vein just inferior and the saphenous nerve just lateral to the artery. A 20 Gauge, 120 mm, non-cuttings tip echogenic needle (SonoPlex STIM, Germany) needle was introduced in-plane, and 2 to 3 mL of LA bolus (0.25 % Bupivacaine) was used to confirm proper needle placement in the adductor canal near the saphenous nerve. Then, a bolus of 20 ml of Bupivacaine 0.25 % was injected through the needle
Continuous adductor canal block	single-shot adductor canal block	a catheter was secured in place using Tegaderm. The catheters were connected to a pump that infused local anesthetic, 20 mL of 0.25 % bupivacaine, followed by 48 hours of continuous infusion of 0.125 % bupivacaine at 5 mL/h.

Primary Outcome Measures

Name	Time	Method
postoperative pain scores by visual analogue score	48 hours	visual analogue score is a straight, vertical 10-cm line with the bottom point representing "no pain" = (0cm) and the top point representing "the worst pain you could ever have" = (10 cm).

Secondary Outcome Measures

Name	Time	Method
the 30-Second Chair test	48 hours	determines how many times a person can rise from a chair and sit down again in 30 seconds while keeping their arms crossed over their chest
six-minute walking test	48 hours	calculates the distance that can be walked in 6 minutes
time to up and go test (minutes)	48 hours	determines how long it takes a person to get out of a chair

Trial Locations

Locations (2)

Aswan University Hospital; 🇪🇬 Aswan, Egypt

Huda Fahmy; 🇪🇬 Aswan, Egypt