EUCTR2015-003286-28-IT进行中（未招募）1 期
A Phase I/ II Study to Evaluate the Safety and Preliminary Efficacy of Nivolumab in Combination with Brentuximab Vedotin in Subjects with Relapsed Refractory Non Hodgkin Lymphomas with CD30 Expression - CheckMate 436: CHECKpoint pathway and nivolumab clinical Trail Evaluation
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 170
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Relapsed/refractory diffuse large B cell lymphoma (DLBCL),
- •relapsed/refractory peripheral T cell lymphoma (PTCL) (all subtypes
- •excluding anaplastic large cell lymphoma), relapsed/refractory
- •Cutaneous T cell lymphoma (CTCL) mycosis fungoides/sezary syndrome
- •(MF/SS), relapsed/refractory primary mediastinal B lymphoma (PMBL),
- •and relapsed/refractory mediastinal gray zone lymphoma (MGZL)
- •Expression of CD30
- •Subjects must be 18 years or older (= 15 years for PMBL)
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 85
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 80
排除标准
- •- Location of the NHL in the central nervous system (CNS)
- •- Positive test for autoimmune disease
研究者
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