Skip to main content
Clinical Trials/NCT05085743
NCT05085743
Completed
Not Applicable

The Prediction of Proper Depth of Endotracheal Tube Fixation Before Intubation by Using Deep Convolutional Neural Networks and Chest Radiographs

Chang Gung Memorial Hospital1 site in 1 country595 target enrollmentNovember 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intubation
Sponsor
Chang Gung Memorial Hospital
Enrollment
595
Locations
1
Primary Endpoint
The lip to carina length predicted by AI model
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Malposition of an endotracheal tube (ETT) may lead to a great disaster. Developing a handy way to predict the proper depth of ETT fixation is in need. Deep convolutional neural networks (DCNNs) are proven to perform well on chest radiographs analysis. The investigators hypothesize that DCNNs can also evaluate pre-intubation chest radiographs to predict suitable ETT depth and no related studies are found. The authors evaluated the ability of DCNNs to analyze pre-intubation chest radiographs along with patients' data to predict the proper depth of ETT fixation before intubation.

Detailed Description

This was a retrospective, IRB-approved study using chest radiographs images obtained from Picture Archive and Communication System (PACS) at Chang Gung Memorial Hospital, Linkou branch, Taiwan. A total of 595 de-identified patients' chest radiographs was obtained for this study. The inclusion criteria for this study are patients 18 years or older who were orotracheal intubated within November 2019 to October 2020 and had taken chest radiographs before and immediately after the intubation (\<24 hours). Both pre-intubation and post-intubation chest radiographs of a same patient were obtained. Clinical data including age, sex, body height, body weight, depth of ETT fixation were also recorded. All ETT tip to carina distance was manually measured by a same anesthesiologist from post-intubation films and documented. Lip to carina length of each patient can be calculated by adding ETT fixation depth and ETT tip to carina distance. Pre-intubation chest radiographs (n=595) along with clinical data including age, sex, body height, body weight, and measured lip to carina length are collected for model building. For this study, 476/595 (80%) of those were used for training and 119/595 (20%) for validation randomly selected by AI model. In training process, images and related clinical data along with the measured lip to carina length are fed into and used to fit out AI model. Then, in validation process, the investigators evaluate the model accuracy and efficacy of predicting the lip to carina length with images and clinical data of those unforeseen cases.

Registry
clinicaltrials.gov
Start Date
November 1, 2019
End Date
October 31, 2020
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Chang Gung Memorial Hospital
Responsible Party
Principal Investigator
Principal Investigator

Po Jui Chen

medical doctor

Chang Gung Memorial Hospital

Eligibility Criteria

Inclusion Criteria

  • 18 years or older
  • orotracheal intubated within November 2019 to October 2020
  • had taken chest radiographs before and within 24hr after intubation

Exclusion Criteria

  • Bad chest radiographs quality that patients' carina can not be recognized
  • Patient with bronchial insertions found in post-intubation films
  • Nasal intubation

Outcomes

Primary Outcomes

The lip to carina length predicted by AI model

Time Frame: 1 minute after DCNNs analysis

The mean absolute error of AI-predicted length in comparison with measured length is used to evaluate AI performance

Secondary Outcomes

  • Rate of endotracheal tube malpositioning according to AI model recommendation(1 minute after DCNNs analysis)

Study Sites (1)

Loading locations...

Similar Trials