A Clinical Study to Evaluate the Comparative Efficacy of Rasnadi Gutika along Chandrakala Lepa with Intra-articular Methylprednisolone acetate Infiltration in Sandhigata Vata(Janu sandhi)w.s.r.to Osteoarthritis(Knee joint)
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change in WOMAC total score (at time of baseline and at end of the treatment)
研究概览
简要总结
The trial is in the early phase and is not yet started.the present study the drugs Rasnadi Gutika (Ref.AFI,part3,page111)contains Rasna,Guggulu,Sarpi.according to Ayurveda ,Rasna is a well known drug for vatashamana aswell as have anti-inflammatory,analgesic,antioxidant effect.Guggulu is also vatahara,shoolahara.Sarpi is vatashamaka and brumhaniya.
Chandrakala lepa (Ref-AFI,part3,page225)contains Madhuchhista,Sveta Maricha,Coconut oil and Karpoora.Madhuchhista and Coconut oil being snigdha in nature decreases rukshata in joints.Sveta Maricha and karpoora are shoolanashaka and effective in Sandhigata vata.
Therefore both above drugs are taken into specific disease condition for the hypothesis that to act effectively for the proper samprapti vighatana by alleviating vata and shoola which are main complaints of diseases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 50.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients fulfilling the diagnostic criteria of OA recommended by American college of Rheumatology.
- •Patients with following radiological findings-definite osteophytes and normal joint space or moderate osteophytes and joint space reduction.
- •Patienys willing for trial.
排除标准
- •Patients having history of trauma,any previous surgery in target knee,knee infection.
- •Patients with systemic disorders 3)ICTC and HBsAg psoitive patients 4)Patients not willing for trial.
结局指标
主要结局
Change in WOMAC total score (at time of baseline and at end of the treatment)
时间窗: Total 8 weeks
次要结局
- Change in WOMAC stiffness domain score.(Change in WOMAC physical function domain.)
研究者
Prof Anil Kumar Sharma
R.G.G.P.G.Ayurvedic college and hospital Paprola.