Hypertensive Disorders of Pregnancy in Adolescence and the Primipaternity Concept. Cases and Control Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- Presence of a primipaternity factor
研究概览
简要总结
Hypertensive disorders of pregnancy are one of the most frequent complications of pregnancy, being a serious health problem around the world.
Previous studies have suggested that there is an association between a short period of exposure to paternal sperm of a new sexual partner and the development of an immunological reaction that could trigger a hypertensive disorder of pregnancy. For this reason we want to study the relationship between the primipaternity concept (exposure to male antigens present in semen over a short period of time previous to the pregnancy) and the development of preeclampsia in adolescents.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 19 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •19 year old or less
- •Pregnancy > 24 weeks at the moment of delivery
排除标准
- •20 years old or more.
- •Pregnancy < 24 weeks at the moment of delivery
结局指标
主要结局
Presence of a primipaternity factor
时间窗: Two months
The presence of primipaternity factor. They include: 1. Sexual Cohabitation (timeframe between first sexual intercourse and pregnancy \< 4 months)without the use of a barrier contraceptive. 2. Oral sex with ejaculation (previous to pregnancy \< 4 months).
次要结局
- Maternal complications(Two months)
研究者
Osvaldo A. Reyes T.
MD
Saint Thomas Hospital, Panama