Application of Biomarkers in Neurological Diseases
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- mRS score in 90 days
研究概览
简要总结
To explore the predictive and diagnostic role of biomarkers in patients with neurological diseases.
详细描述
With the rise and continuous development of omics technology and bioinformatics technology, some scholars have applied proteomics technology and metabolomics technology to study the brain tissue, plasma and CSF of patients with nervous system diseases, so as to screen out potential biomarkers, with a view to providing new research ideas for pathogenesis and early diagnosis of neurological diseases. At present, the research on some novel biomarkers is still in its infancy, and many key problems remain to be solved. It is necessary to further determine the expression level of biomarkers in normal human body and the characteristics of biomarkers in patients with neurological diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with neurological diseases;
- •Subjects or legal agents agree to participate in the study and sign the informed consent.
排除标准
- •Participating in other clinical investigators;
- •Unwilling to be followed up or poor treatment compliance;
- •Other conditions considered unsuitable for inclusion by the researchers.
结局指标
主要结局
mRS score in 90 days
时间窗: 3 months
The proportion of 3-month good functional outcome (mRS Score 0-2) in patients with neurological diseases was evaluated by mRS Score
次要结局
未报告次要终点
研究者
Yi Yang
Associated Dean of First Hospital of Jilin University
The First Hospital of Jilin University