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Clinical Trials/NCT05875623
NCT05875623
Active, not recruiting
Not Applicable

Impact of Medications Review on Potentially Inappropriate Medications and Clinical Outcomes Among Hospitalized Older Adults: A Randomized Controlled Trial (REVMED RCT) Protocol

Monash University1 site in 1 country500 target enrollmentJuly 6, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Deprescriptions
Sponsor
Monash University
Enrollment
500
Locations
1
Primary Endpoint
Number of potentially inappropriate medications
Status
Active, not recruiting
Last Updated
11 months ago

Overview

Brief Summary

The goal of this randomized controlled trial is to assess the effectiveness of a pharmacist-led medication review using the locally developed Malaysian Potentially Inappropriate Prescribing Screening tool in Older Adults (MALPIP), an explicit criteria in hospitalized older adults. The main questions it aims to answer are:

  1. The effectiveness of the intervention in reducing the number of PIMs and chronic medications after discharge
  2. The impact of the intervention on quality of life, falls events, emergency department visits, readmissions and survivals

Researchers will compare the control group to see if there is corresponding changes to the outcomes specified above.

Registry
clinicaltrials.gov
Start Date
July 6, 2023
End Date
December 30, 2025
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shaun Lee Wen Huey

Professor

Monash University

Eligibility Criteria

Inclusion Criteria

  • Patients aged 60 years and above
  • Taking more than five regular drugs
  • Having at least one chronic medical condition
  • Ability to understand and speak Malay, English, or Mandarin language

Exclusion Criteria

  • Admitted for end-of-life care
  • Diagnosed with terminal illness
  • Diagnosed with active cancer
  • Participated in another drug trial
  • Refused or unable to give consent
  • Visited the Emergency Department without admission to ward
  • Readmitted and have been previously enrolled in the trial

Outcomes

Primary Outcomes

Number of potentially inappropriate medications

Time Frame: Admission up to 18 months

Number of chronic medications

Time Frame: Admission up to 18 months

Study Sites (1)

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