Compare efficacy of POCUS vs traditional methods in fluid management in early post transplant period
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To quantify fluid status in immediate post transplant using traditional, pocus and bioimpedance.
研究概览
简要总结
Renal transplantation improves survival and quality of life , hence it is modality of choice for
treating ESRD patients. “The kidneys receive approximately 25% of the body’s total cardiac
output (CO) which is essential for maintaining the osmolarity of body fluids and for
maintaining extracellular volume. Patients with renal failure often have electrolyte
imbalances and they tend to oscillate in their volume status between hypovolemia and
hypervolemia “.This results in a very narrow safety margin for intravenous fluid resuscitation and
maintenance. Patients undergoing kidney transplantation are at risk of developing DGF, acute
kidney injury (AKI) and fluid overload in the post operative period.†Fluid management
during intraoperative and perioperative period affects hemodynamics and perfusion of the
graft and may pose the risk of peri-operative cardiac events . Fluid therapy if given
adequately decrease delayed graft function.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient undergoing live related renal transplantation.
排除标准
- •Unwilling to give consent Patients with severe valvular lesions Patients who are multiorgan recipient Patients who is in overt sepsis.
结局指标
主要结局
To quantify fluid status in immediate post transplant using traditional, pocus and bioimpedance.
时间窗: Day 7 of immediate post transplant period
To compare the efficacy of traditional versus pocus finding in diagnosis of fluid excess.
时间窗: Day 7 of immediate post transplant period
次要结局
- Establish algorithm for fluid management in immediate post transplant period.(With in one year from commencement of study.)
研究者
Dr Katyayani
PGIMER Chandigarh