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临床试验/NCT03162692
NCT03162692Unknown不适用

Preoperative Anxiety's Incidence and Related Factors in Surgical Patients

Xuzhou Medical University1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2017年4月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
2,000
试验地点
1
主要终点
Anxiety level

研究概览

简要总结

Preoperative anxiety is often described as an uncomfortable, tense unpleasant mood before surgery, an emotional response to a potential challenge or threat to reality. Data show that adult patients with preoperative anxiety rate of 30-40%. The main reason for the occurrence of patients for surgery, anesthesia and other factors of fear. Preoperative anxiety itself is not a mental illness, but studies have confirmed that the occurrence of preoperative anxiety and postoperative complications were positively correlated, and the existence of preoperative anxiety in patients with conventional postoperative analgesic effect is poor. At present, there are still few studies on the relationship between preoperative anxiety and postoperative complications and analgesia. At the same time, there is a lack of large sample size to study the incidence of preoperative anxiety and its related predictors.

详细描述

Surgical patients often have varying degrees of preoperative anxiety.The aim of this study was to determine the incidence of preoperative anxiety and related predictors, and to evaluate the effect of anxiety on anesthesia and postoperative pain and prognosis. The study also showed that prostaglandin, catecholamines, cortex Effects of alcohol and inflammatory cell level on postoperative pain in patients with preoperative anxiety.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18-70 years old
  • Sign that informed consent is willing to participate in the study
  • Education: primary school and above
  • 1 days after elective general anesthesia surgery
  • ASA score grade I-III

排除标准

  • Emergency surgery
  • Severe mental illness patients (such as anxiety, depression, schizophrenia, etc.)
  • Taking anti-anxiety or antidepressants (benzodiazepines, tricyclic antidepressants, selective serotonin inhibitors, monoamine oxidase inhibitors, etc.)

结局指标

主要结局

Anxiety level

时间窗: All patients are evaluated one day before surgery

as measured by STAI (state-trait anxiety questionnaire)

次要结局

  • VAS pain score(at 3 hours, 6 hours, 24 hours, 48 hours after surgery)

研究者

发起方
Xuzhou Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jin Dong Liu

Chief physician and Associate Professor

Xuzhou Medical University

研究点 (1)

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