ISRCTN89405844进行中（未招募）Unknown
Exacerbation prevention in COPD - effect of home high-flow therapy versus usual care on hospital readmission or death after an acute chronic obstructive pulmonary disease (COPD) exacerbation: a UK-based multicentre randomised clinical trial
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 入组人数
- 502
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Severe exacerbation of COPD*
- •2. Age 40-80 years
- •3. Diagnosis of COPD as defined by GOLD criteria
- •4. Smoking history of >10 pack years
- •5. Forced expiratory volume in 1 second (FEV1) <80% predicted
- •6. FEV1/FVC < 0.7**
- •*Severity defined by admission to hospital (acute admissions unit or hospital ward)
- •**post bronchodilator
排除标准
- •1. Significant obesity (BMI >35kg/m²)
- •2. Clinically significant obstructive sleep apnoea syndrome requiring PAP therapy (see screening procedures for more detail)
- •3. Major non-COPD chronic co-morbidity that may significantly contribute to risk of readmission or death within 1 year
- •4. Home PAP or NIV therapy
研究者
相似试验
已完成
4 期
Prevention of exacerbations in patients with COPD through vitamin D supplementation: a randomized controlled trialchronic obstructive pulmonary disease10024967NL-OMON44715Vrije Universiteit Medisch Centrum240
Unknown
4 期
Exacerbation Prevention GOLD IV COPD With Non Invasive Mechanical VentilationChronic Obstructive Pulmonary DiseaseNCT01481727National Institute of Respiratory Diseases, Mexico20
已完成
不适用
Study to Identify the Reduction of Exacerbations Resulting in Hospital Admission in Patients With COPD.COPD ExacerbationNCT05440188Universidad Autonoma de Madrid80
已完成
不适用
Home-based Treatment of Patients With Chronic Obstructive Pulmonary Disease (COPD)COPDNCT00702078St. Olavs Hospital172
终止
不适用
Efficacy of High Flow Therapy in COPD At HomeCOPDNCT02230020Johns Hopkins University8