To find out whether ultrasound of various veins of body can predict onset of acute kidney injury in critically ill septic patients admitted to intensive care unit
Not Applicable
- Conditions
- Health Condition 1: R652- Severe sepsis
- Registration Number
- CTRI/2021/03/031717
- Lead Sponsor
- Department of Anaesthesiology Pain Medicine and Critical care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged more than 18 years being admitted to ICU with diagnosis of/ or develop sepsis/septic shock (as per sepsis 3)
Exclusion Criteria
1.Known cases of cirrhosis with portal hypertension,
2.Inadequate window
3.IVC thrombus
4.Already having AKI/CKD
5.Known case of right heart compromise (diagnosed on previous echo),
6.Known case of Pulmonary artery hypertension,
7.Known case of Tricuspid regurgitation,
8.Abdominal compartment syndrome
9.Abdominal surgery
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess correlation of serial VEXUS score and AKI in patients with sepsis/septic shock in ICUTimepoint: Day 0,2,3,5 after ICU admission or need of renal replacement therapy which ever is earlier
- Secondary Outcome Measures
Name Time Method Whether addition of RRI to VEXUS score will add sensitivity to predict AKITimepoint: Day 0,2,3,5 after ICU admission or need of renal replacement therapy which ever is earlier;Whether change in VEXUS score predicts AKI earlier then creatinine or urine output changeTimepoint: Day 0,2,3,5 after ICU admission or need of renal replacement therapy which ever is earlier;Whether individual components of VEXUS score correlated with AKITimepoint: Day 0,2,3,5 after ICU admission or need of renal replacement therapy which ever is earlier;Whether VEXUS score correlate with all-cause mortality at ICU dischargeTimepoint: At ICU discharge;Whether VEXUS score correlate with ICU stay & mechanical ventilation daysTimepoint: At discharge/death from ICU;Whether VEXUS score correlate with requirement of Renal Replacement TherapyTimepoint: ay 0,2,3,5 after ICU admission or need of renal replacement therapy which ever is earlier