A study of how stroke can impact how we think and feel in the long term. How common is it to have problems with processing information and feelings after stroke and what are the underlying causes?

Not Applicable

Completed

• Conditions: Prevalence of psychological consequences of stroke; Mental and Behavioural Disorders

• Registration Number: ISRCTN81038194
• Lead Sponsor: niversity of Oxford

Brief Summary

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/35342816/ (added 28/03/2023) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/38036966/ (added 05/12/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-16
• Study Completion: 2022-10-25
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

OX-CHRONIC directly leverages existing data. A cognitive screening programme based within the acute stroke unit, capturing the Oxfordshire area has been ongoing since 2012. Participants in this study have been assessed for stroke specific cognitive impairments during acute recovery and at six-month follow-up. Participants agree to be followed up 6 months later with a home visit to assess psychological consequences of stroke and quality of life. Participants who completed the follow-up and gave explicit opt-in consent for re-contacting for further research will be contacted to take part in this two-year follow-up study. Importantly, there is a minimum two-year interval between stroke and the first new assessment for OX-CHRONIC.

Exclusion Criteria

1. The participant is too unwell to be able to stay awake or concentrate for 30 minutes
2. The participant or consultee/proxy has insufficient English comprehension to complete assessments,

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Dementia status using DSM-5 criteria and based on medical records, cognitive testing and impairment in function of activities of daily living assessed by two trained physicians at wave 1 and wave 2<br>2. Domain specific impairment is measured using the Oxford Cognitive Screen (OCS) at wave 1 and wave 2.<br>3. Global cognitive impairment is measured using the Montreal Cognitive Assessment (MoCA) at wave 1 and 2.<br>4. Activities of daily living is assessed using Nottingham Extended ADL at wave 1 and 2.