NL-OMON53593招募中4 期
Preoperative sodium glucose cotransporter 2 inhibitors for prevention of postoperative acute kidney injury in cardiac surgery patients - a randomized, placebo-controlled, multi-centre, phase IV clinical trial - The MERCURI-2 trail
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 784
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. >18 years old 2. Undergoing elective cardiac surgery. 3. Providing informed
排除标准
- •1. Current treatment with SGLT2 inhibitors 2. Reduced kidney function at
- •baseline with eGFR < 20 ml/min at time of inclusion 3. Diabetes Mellitus Type 1
- •4. History of diabetic keto acidosis 5. Diabetes Mellitus Type 2 with BMI<25
- •for people with type 2 diabetes who are using multiple daily insulin injections
- •(both short and long-acting insulin) 6. Systolic blood pressure < 100 mmHg at
- •time of inclusion 7. Emergency surgery, defined as in need of surgery for
- •medical reasons < 7 days, i.e. *S1-4* according to the Amsterdam UMC
- •classification 8. Female of child-bearing potential who is pregnant,
- •breast-feeding or intend to become pregnant or is not using adequate
- •contraceptive methods 9. Known or suspected allergy to trial products or other
- •drugs in the same class
研究者
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