White Box Modeling of Self-Determine Sequence Exercise Program Among Sarcopenic Elderly: Uncovers a Novel Strategy Overcoming Decline of Skeletal Muscle Area
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 392
- 试验地点
- 1
- 主要终点
- Using a bioelectrical impedance body composition analyzer with a multifrequency device to investigate the change of relative skeletal muscle mass index in sarcopenic elderly.
研究概览
简要总结
Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function. Resistance exercise, Taichi exercise and the hybrid exercise program consisting of the two aforementioned methods have been demonstrated could increase the skeletal muscle mass of the elderly with sarcopenia. However, note that the above contents may be performed in a different order in a treatment, equally important but less well understood is the sequence in which it should be performed. Surprisingly, the exercise sequence has not been comprehensively investigated. Therefore, investigators designed a self-ordered exercise program combining resistance exercise, tai chi and a hybrid exercise program to investigate whether the decline in skeletal muscle area could be better overcome and the reversal of sarcopenia in elderly with sarcopenia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •satisfied the Asian screening criteria for sarcopenia by the Asian Working Group for Sarcopenia;
- •age higher than 60 but less than 75 years of age.
排除标准
- •with serious illness or breathing failure;
- •with neuro-muscular diseases;
- •taking medication that has an effect on the function of skeletal muscles;
- •with conditions relating to the neurological system or the mental health;
- •in another scheduled training plan.
结局指标
主要结局
Using a bioelectrical impedance body composition analyzer with a multifrequency device to investigate the change of relative skeletal muscle mass index in sarcopenic elderly.
时间窗: Month 6
Participants will receive a relative skeletal muscle mass index test before and after the intervention to assess the change from baseline relative skeletal muscle index at 6 months.
Using quantitative CT to investigate the change of skeletal muscle area in sarcopenic elderly.
时间窗: Month 6
Participants will receive quantitative CT scans before and after the intervention to assess the change from baseline skeletal muscle area at 6 months.
Using a Jamar hydraulic hand dynamometer to investigate change of handgrip in sarcopenic elderly.
时间窗: Month 6
Participants will receive a handgrip strength test before and after the intervention to assess the change from baseline handgrip strength at 6 months.
次要结局
- Collect participants' self-evaluation of their life state and physical state.(Month 6)
- Collect video of participants throughout the intervention.(Month 6)
研究者
Guang Yang, Prof. Dr.
Prof.Dr.
Northeast Normal University