Exercising Wrist muscles assisted with robotic hand and brain stimulation therapy in hospital set up
Phase 2
- Conditions
- Health Condition 1: G819- Hemiplegia, unspecified
- Registration Number
- CTRI/2020/05/024992
- Lead Sponsor
- Ministry of Defense
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Single lesion
Chronic stroke(3-120months)
cortical/subcortical
Ischemic/Hemmorhagic Stroke
Modified Ashworth Scale (1 1+ 2 3)
Brunnstorm Stage (3-5)
Wrist extension EMG activity present
Able to give informed consent and follow instructions to execute training task
Mini Mental State Examination(24-30)
Exclusion Criteria
Contraindications to TMS,progressive neurological or cognitive disorders impringing with assessment scales
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical Scales of Rehabilitation, Modified <br/ ><br>Ashworth Scale, Brunnstorn Stage, <br/ ><br>Electromyography changes, <br/ ><br>Cortical Excitability, <br/ ><br>Motor Evoked Potential Changes, <br/ ><br>fMRI changesTimepoint: Clinical Scales of Rehabilitation and <br/ ><br>NeuroPhyiological Signals will be taken at 2 time points, 1 at time of enrollment and 2 at end of intervention at 4weeks
- Secondary Outcome Measures
Name Time Method Barthel Index (BI), Modified Rankin Scale, Motor Assessment Scale(MoAS), FMA, Edinburg Laterality index, Stroke rehabilitation Motivation ScaleTimepoint: Clinical Scales of Rehabilitation will be taken at 2 <br/ ><br>time points, 1 at time of enrollment and 2 at end of intervention (4weeks)