A randomised controlled trial of triclosan coated sutures in primary total hip and total knee arthroplasty
Not Applicable
Completed
- Conditions
- Primary total hip and knee replacement patientsSurgery
- Registration Number
- ISRCTN21430045
- Lead Sponsor
- niversity College London (UK)
- Brief Summary
2019 results in: http://dx.doi.org/10.5312/wjo.v10.i7.268
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Adult patients undergoing unilateral primary total hip or knee replacement
Exclusion Criteria
1. Undergoing unilateral primary total hip or knee replacement for trauma
2. Undergoing a revision procedure or with a previous incision in the operative field
3. History of tendency for keloid formation
4. Allergy to triclosan/vicryl
5. Bleeding tendency (e.g. haemophilia and platelet disorders) or on regular anticoagulation treatment (e.g. warfarin, treatment dose of low molecular weight heparin (LMWH) or conventional heparin)
6. Underlying malignancy and immunocompromised status
7. Dementia and mental illnesses preventing informed consent
8. Children (age <18 years)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Healing characteristics, using the ASEPSIS wound scoring method devised in 1986 by Wilson et al at University College London Hospitals
- Secondary Outcome Measures
Name Time Method Secondary objectives include recording data pertaining to demographics, procedure type, length of operating time, plus patient factors believed to influence wound healing and infection risk. Complications associated with using both sutures and their influence on early discharge will also be noted, as this may result in improved patient outcomes, cost effectiveness and long term prosthesis survival.