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Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4

Phase 2
Completed
Conditions
Cocaine-Related Disorders
Registration Number
NCT00000301
Lead Sponsor
University of California, Los Angeles
Brief Summary

The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested."

Detailed Description

16-week participation plus a 2 weekk lead-in period. Participants are assigned randomly to placebo or amantadine. Participants attend group meeting 3 times/week

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

M/F, ages 18-65. cocaine dependence according to DMS-IV criteria. Self-reported use within the last 30 days. Agreeable to conditions of the study and signed informed consent.

Exclusion Criteria

Psychiatric disorder that requires medication therapy, history of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cocaine craving
Psychosocial progress
Cocaine use
Retention
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Friends Research Institute

🇺🇸

Los Angeles, California, United States

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