Comparison of two different techniques for loss of conciousness in children undergoing eye surgeries
- Conditions
- Retinal detachment with retinal break,
- Registration Number
- CTRI/2018/10/016204
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
For many decades, inhalational agents have been commonly used for the maintenance of anesthesia in pediatric population. However, with the introduction of newer intravenous induction agents and short acting opioids have revolutionized the day care anesthesia practice and subsequently TIVA (total intravenous anesthesia) has gained popularity in this patient population. (1,2,10)
Vitreoretinal surgeries are performed in children with retinal abnormalities and generally last for a long duration of time. Using inhalational anesthesia with Sevoflurane for such a prolonged duration has been associated with emergence agitation. (3,4)
Manual verses TCI infusion of propofol for maintenance of anesthesia has been found comparable in children but the use of TCI is considered safe and easily titrable with BIS monitoring. (5,8)
The use of TIVA with propofol infusion for maintenance of anesthesia in adults has shown to have a clear headed recovery.(13)
Earlier dedicated pediatric TCI infusion model were not in common practice .Now introduction of PK based TCI models like Pedfussor and Kataria available for children.(7,11,12)
In our knowledge No study has been done so far to compare sevoflurane and TCI propofol infusion for maintainance of anesthesia in pediatric ophthalmic surgeries.
We hypothesize that aneathesia administered using TCI propofol infusion in children, recovery will be clear headed and early discharge from PACU as compared to standard inhalational technique using Sevoflurane
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 50
ASA I/II Elective vitreo-retinal surgeries Duration of surgery >45 minutes and <3hrs Written informed consent from parents.
children with Cardiac, hepatic and renal diseases Congenital heart disease Mental retardation Syndromic children Premedication with sedatives Surgeries <45 minutes and >3hrs Refusal to give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparision of PACU stay and discharge time (from switching off of anaesthetic agents to achievement of Modified Aldrete score of 9 or more) of two anaesthetic techniques : TCI vs Inhalational in children undergoing vitreo-retinal surgery Post operative 0min,10min,20min,40min and 60 min.
- Secondary Outcome Measures
Name Time Method Induction Characteristics Time of induction / loss of conciusness/verbal command
Trial Locations
- Locations (1)
Dr Rajendra Prsad Center for ophthalmic sciences AIIMS New Delhi
🇮🇳South, DELHI, India
Dr Rajendra Prsad Center for ophthalmic sciences AIIMS New Delhi🇮🇳South, DELHI, IndiaDr Nishant PatelPrincipal investigator8510955882pateldrnishant@gmail.com