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临床试验/NCT02474628
NCT02474628已完成不适用

Consistencies in Responses to Sodium Bicarbonate Supplementation: a Randomised, Repeated Measures, Counterbalanced and Double-blind Study

University of Sao Paulo1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2013年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1
主要终点
blood pH

研究概览

简要总结

Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. The investigators aim to determine the consistency of metabolic and exercise responses following repeated administration of sodium bicarbonate (SB). Design and Methods: 15 physically active males will complete six cycling capacity tests at 110% of maximum power output (CCT110%) following ingestion of either 0.3 g∙kg-1Body Mass of SB (4 trials) or placebo (PL, 2 trials). Blood pH, bicarbonate, base excess and lactate will be determined at baseline, pre-exercise, post-exercise and 5-min post-exercise. Total work done (TWD) will be recorded as the exercise outcome.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •recreationally active males

排除标准

  • •use of dietary supplements in the past 6 months
  • •the presence of any musculoskeletal disorder
  • •the use of anabolic steroids

研究组 & 干预措施

Sodium bicarbonate

Experimental

0.3 g∙kg-1body mass of sodium bicarbonate

干预措施: sodium bicarbonate (Dietary Supplement)

Placebo

Placebo Comparator

0.3 g∙kg-1body mass of calcium carbonate

干预措施: calcium carbonate (Dietary Supplement)

结局指标

主要结局

blood pH

时间窗: 5 min after a physical exercise test

次要结局

  • blood lactate(5 min after a physical exercise test)
  • blood bicarbonate(5 min after a physical exercise test)
  • anaerobic exercise capacity(4 hours after supplementation)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bruno Gualano

Professor

University of Sao Paulo

研究点 (1)

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