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Estimation of the MCID for Patients With Knee Osteoarthritis

Not Applicable
Completed
Conditions
Knee Osteoarthritis
Interventions
Other: Exercise
Registration Number
NCT06034665
Lead Sponsor
Istanbul University
Brief Summary

Background: The effect of exercise on knee osteoarthritis (OA) is often evaluated with patient-reported scales. The Minimal Clinically Important Difference (MCID) values of these scales are needed to understand the change in patients after treatment and to manage the treatment.

It is also one of the most important data in calculating the MCID sample size. Aim: In the literature, MCID studies for exercise applied to knee OA are limited especially for those who did not undergo surgery. Thus new studies are needed.

Method: 100 patients who were diagnosed with knee osteoarthritis will be recruited for the study. Participants will be included in an exercise program tailored to their needs for 15 sessions. WOMAC, OKS, LEFS scales will be used also knee range of motion will be assessed in the baseline, after treatments and in the 4th month follow up.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
94
Inclusion Criteria
  • To be diagnosed with knee OA according to the criteria of the American Society of Rheumatology (ACR) (Diagnosis of primary knee OA)
  • Stage 2 or 3 according to Kellgren Lawrence radiological staging criteria
  • Participants with age between 50 and 70 years old
  • Being able to walk without using an assistive device
  • Having a body mass index of less than 30 kg/m²
  • Pain severity is between 3 and 7 according to the Numerical Pain Rating Scale
Exclusion Criteria
  • Patients who received physical therapy or intra-articular injections in the last 6 months
  • Receiving an indication for surgery
  • Have severe hearing, vision and speech impairment
  • Having serious systemic and cardiovascular diseases that interfere with exercise
  • Having a lower extremity deformity
  • Patients with acute inflammation of the knee

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
ExerciseExerciseAll patients will receive an exercise rehabilitation program tailored to their needs.
Primary Outcome Measures
NameTimeMethod
LEFSBaseline, after 15 session and 4 months follow up

Lower Extremity Functional Scale

WOMACBaseline, after 15 session and 4 months follow up

Western Ontario and McMaster Universities Osteoarthritis Index

Knee Range of MotionBaseline, after 15 session and 4 months follow up

Range of motion assessment with goniometer

KOOSBaseline, after 15 session and 4 months follow up

Knee Injury and Osteoarthritis Outcome Score

Secondary Outcome Measures
NameTimeMethod
30s sit to stand testBaseline, after 15 session and 4 months follow up

For functional assessment, patient sit and stand for 30 seconds

Trial Locations

Locations (1)

Istinye University Physiotherapy and Rehabilitation Application and Research Center

🇹🇷

Istanbul, Turkey

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