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临床试验/NCT03836781
NCT03836781已完成2 期

Comparison of Teh TEMPEffect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist.

Amirhossein Farahmand1 个研究点 分布在 1 个国家目标入组 2 人开始时间: 2018年4月10日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
2
试验地点
1
主要终点
Pocket depth

研究概览

简要总结

In this study, 40 patients with a history of Mild- Periodontitis who were diagnosed with clinical and radiographic findings showed that all of the periodontal parameters before the treatment, during the treatment period Then, scaling & Root planing and oral hygiene instructions were given to the patients, and after 2 weeks, the patients who received the study were randomly divided into two groups (Balanced Block Randomization) with four blocks according to the visit time. To group A, oral chlorohexidine and to B group, the drug Ketorolac was given. 5 mm of the drugs required every 15 days the areas underwent a gingival wash with an insulin syringe, which lasted for 3 months.

详细描述

In this study, 40 patients with a history of Mild- Periodontitis who were diagnosed with clinical and radiographic findings showed that all of the periodontal parameters before the treatment, during the treatment period Then, scaling & Root planing and oral hygiene instructions were given to the patients, and after 2 weeks, the patients who received the study were randomly divided into two groups (Balanced Block Randomization) with four blocks according to the visit time. To group A, oral chlorohexidine (Ghol Darou-Tehran) and to B group, the drug Ketorolac (Exir-Boroujerd) was given. 5 mm of the drugs required every 15 days the areas underwent a gingival wash with an insulin syringe, which lasted for 3 months. Pl, BI, PD were evaluated in the study sessions. At the end of the clinical change, a multiple measure ANOVA test was used to compare the preceding and follow-up sessions in both groups, considering the intervention method as Between subject comparison And measured at the time of measurement as a Repeated Factor.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Care Provider, Investigator)

入排标准

年龄范围
30 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 40 patients with periodontitis chronic and has a 2 molar symmetrically in the lower jaw pockets of the periodontal depth of at least 5 mm and CAL 1-2 mm in at least one of the surfaces of the teeth, were selected

排除标准

  • systemic disease
  • pregnancy or breastfeeding
  • allergy drug used
  • not willing to consent to participate in the study
  • 7-Trismus 8-The type of disease periodontal (Aggressive)
  • History of periodontal treatment in the previous 6 months 10-orthodontic treatment

研究组 & 干预措施

ketorolac 3%

Active Comparator

ketorolac 3% topical subgingival irrigation was put into the periodontal pocket using an insulin syringe

干预措施: Ketorolac (Drug)

chlorhexidine 2%

Other

chlorhexidine 2% topical subgingival irrigation was put into the periodontal pocket using an insulin syringe

干预措施: Chlorhexidine 2% (Drug)

结局指标

主要结局

Pocket depth

时间窗: 3 month

Clinical periodontal measurements to Williams periodontal probe

次要结局

未报告次要终点

研究者

发起方
Amirhossein Farahmand
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Amirhossein Farahmand

assistant prof

Islamic Azad University, Tehran

研究点 (1)

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