Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Number of affected level IV cervical lymph nodes
研究概览
简要总结
Regarding oral cavity cancer, the high incidence of neck metastasis along with its impact on survival and prognosis are in favor of elective neck dissection. Moreover, occult metastases could develop at lower levels in the neck (levels IV-V) Regarding the tongue, the rate of skip (occult) metastasis involving unremoved level IV cervical lymph nodes in squamous cell carcinoma of the tongue ranges from 0 % - 11.4 %. However, no data is available or a correlation between the risk of level IV involvement and the affection of specific tongue subsites or a certain cutoff value of tumor thickness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with squamous cell carcinoma of the tongue and floor of the mouth.
- •Age group: from 15 to 60 years old
- •No sex predilection
排除标准
- •Patients with recurrent squamous cell carcinoma of the tongue and floor of the mouth.
- •Irradiated patients or those taking chemotherapy.
结局指标
主要结局
Number of affected level IV cervical lymph nodes
时间窗: One week : submitted immediately after surgery
In each case the specimen will be assessed for level IV lymph nodes affection
tumor thickness in mellimeters
时间窗: one week: specimens are submitted immediately after surgery
histological assessment of tumor thickness of the resected tumor and assessment of level IV lymph nodes
次要结局
- affected tongue site in relation to level IV cervical lymph nodes(One week)
研究者
Mohamed Shawky
Assistant lecturer
Cairo University