Effects of Lycium Barbarum Supplements on the Progression of Senile Cataract in Hong Kong Chinese Population
- Conditions
- Lens Opacity
- Interventions
- Dietary Supplement: Lycium BarbarumDietary Supplement: Starch
- Registration Number
- NCT01142960
- Lead Sponsor
- The Hong Kong Polytechnic University
- Brief Summary
With the rapid growing aging population, age-related eye diseases including cataract are becoming more prevalent. The demand for cataract surgery and post-surgical care posed enormous financial burdens to the government.
Lycium barbarum contains lutein and zeaxanthin which can filter the phototoxic blue light and neutralize the reactive oxygen species, thus provide a protective effect against cataract formation.
This study aims to determine the effects of Lycium barbarum Supplements on the progression of senile cataract in Hong Kong Chinese elderly.
- Detailed Description
Please note that a manuscript for this study is being prepared. Detailed description will be provided after we come up with the final draft.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 238
- Unlikely to have cataract surgery within 3 years
- Presence of mild to moderate cataract in one or both eyes, graded by Lens Opacities Classification System III (LOCSIII).
- logMAR acuity equivalent to Snellen acuity of 20/63 or better
- no previous history and clinical signs of glaucoma by determining intraocular pressure using applanation Tonometry (no more than 22mmHg)
- no ocular anomalies: amblyopia, binocular anomalies, ocular trauma
- no history of eye surgery, laser treatment, iritis, retinal crystalline deposits, macular degeneration, or optic nerve diseases
- no extended use of systemic or ocular corticosteroid drugs
- no concurrent participation of other systemic or ocular drug intervention study
- diabetes mellitus
- renal failure
- fat malabsorption syndrome
- intestinal surgery history
- chronic diarrhea
- alcoholism
- use of anticoagulants
- regular use of nutritional supplements such as multi-vitamin, mineral and other antioxidant supplements (including Omega-3)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Lycium Barbarum Lycium Barbarum Lycium Barbarum supplement Placebo Starch Starch
- Primary Outcome Measures
Name Time Method Lens Opacity Classification System III (LOCSIII) 3 years
- Secondary Outcome Measures
Name Time Method Visual Acuity 3 years
Trial Locations
- Locations (1)
The Hong Kong Polytechnic University
ðŸ‡ðŸ‡°Hung Hom, Kowloon, Hong Kong