Effects of Preoperative Oral Carbohydrates Loading in Patients at High Risk of Postoperative Nausea and Vomiting Undergoing Spinal Surgery
Phase 4
- Conditions
- Spinal Disease
- Interventions
- Other: oral carbohydrate beverageOther: control group
- Registration Number
- NCT02809950
- Lead Sponsor
- Yonsei University
- Brief Summary
Many patients receiving opioid based analgesia after spinal surgery experience postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with antiemetic agents. Dehydration caused by fasting prior to surgery is associated with the development of PONV. The aim of this study is to investigate the effect of oral carbohydrates loading prior to surgery in patients at high risk of PONV undergoing spinal surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 288
Inclusion Criteria
- female patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅱ
- patient scheduled for elective spine surgery
- no smoking history
Read More
Exclusion Criteria
- hepatorenal disease
- BMI > 35 kg/m2
- gastrointestinal disease
- vomiting within 24h
- administration of antiemetics or opioids within 24 h prior to surgery
- pregnant
- problem with communication
Read More
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description oral carbohydrate beverage group oral carbohydrate beverage - control group control group -
- Primary Outcome Measures
Name Time Method incidence of nausea and vomiting 48 hours
- Secondary Outcome Measures
Name Time Method severity of nausea 48 hours 11-point numerical rating scale (0: no nausea \~10: worst imaginable nausea)
Trial Locations
- Locations (1)
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
🇰🇷Seoul, Korea, Republic of