NCT02809950Unknown4 期
Effects of Preoperative Oral Carbohydrates Loading in Patients at High Risk of Postoperative Nausea and Vomiting Undergoing Spinal Surgery
适应症
干预措施
试验速览
- 阶段
- 4 期
- 入组人数
- 288
- 试验地点
- 2
- 主要终点
- incidence of nausea and vomiting
研究概览
简要总结
Many patients receiving opioid based analgesia after spinal surgery experience postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with antiemetic agents. Dehydration caused by fasting prior to surgery is associated with the development of PONV. The aim of this study is to investigate the effect of oral carbohydrates loading prior to surgery in patients at high risk of PONV undergoing spinal surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •female patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅱ
- •patient scheduled for elective spine surgery
- •no smoking history
排除标准
- •hepatorenal disease
- •BMI > 35 kg/m2
- •gastrointestinal disease
- •vomiting within 24h
- •administration of antiemetics or opioids within 24 h prior to surgery
- •problem with communication
研究组 & 干预措施
oral carbohydrate beverage group
Experimental
干预措施: oral carbohydrate beverage (Other)
control group
Placebo Comparator
干预措施: control group (Other)
结局指标
主要结局
incidence of nausea and vomiting
时间窗: 48 hours
次要结局
- severity of nausea(48 hours)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Preoperative Carbohydrate Loading in Patients Undergoing Day-case CholecystectomyPreoperative CareNCT03757208University of Oulu113
已完成
不适用
Effect of oral carbohydrate on pain, postoperative nausea and vomitingAcute pain.Acute painIRCT201710318433N5Vice Chancellor for Research & Technology, Kashan University of Medical Sciences60
已完成
不适用
Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery PatientsNon Small Cell Lung CancerFastingPostoperative PneumoniaNCT05005091Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital94
已完成
不适用
Preoperative Oral Carbohydrate and Postoperative Recovery in Diabetic PatientsGastrointestinal SurgeryNCT03204344Dong-Xin Wang65
已完成
不适用
Preoperative Administration of Oral Carbohydrate Drink, Neutrophil/Lymphocyte Ratio and Postoperative ComplicationsNeutrophilLymphocytePostoperative ComplicationsNCT05301985Nermina Rizvanović60