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Clinical Trials/NL-OMON46147
NL-OMON46147
Completed
Not Applicable

A Multicentre, Prospective, Longitudinal, Observational Natural History Study to Evaluate Disease Progression in Subjects with Usher Syndrome type 1B (USH1B) - Natural history of Usher syndrome type 1B

Oogziekenhuis Rotterdam0 sites10 target enrollmentTBD
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ConditionsUsher syndrome type 1B10015917

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Usher syndrome type 1B
Sponsor
Oogziekenhuis Rotterdam
Enrollment
10
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational non invasive

Investigators

Sponsor
Oogziekenhuis Rotterdam

Eligibility Criteria

Inclusion Criteria

  • •Informed consent
  • •Diagnosed with USH1
  • •Molecular diagnosis of USH1B due to MYO7A mutations (homozygotes or compound heterozygotes)
  • •Age \>\= 8 years
  • •Visual acuity \>\= 20/640 in at least one eye

Exclusion Criteria

  • •Unable to communicate with suitable verbal/auditory and/or tactile sign language
  • •Participation in clinical study with investigational drug in past 6 months
  • •Pre\-existing ocular conditions that would interfere with the interpretation of study
  • •endpoints (e.g. glaucoma, corneal or significant lenticular opacities, cystoid macular oedema, macular hole) in both eyes
  • •Complicating systemic diseases in which the disease itself, or the treatment for the disease,
  • •can alter ocular function
  • •Prior ocular surgery within 3 months

Outcomes

Primary Outcomes

Not specified

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