A multicenter, randomized, controlled study of a novel detoxifying, detoxifying, detoxifying, detoxifying, and regulating vaginal microecology in the treatment of persistent cervical human papillomavirus infection at high risk

Phase 1

Recruiting

• Conditions: Cervical high risk human papillomavirus (HPV) infection continues

• Registration Number: ITMCTR2000004006
• Lead Sponsor: Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

(1) Between the ages of 18 and 55, married or sexually active women;
(2) Had been infected with HPV virus for more than one year;
(3) After sampling and examination in our hospital, the classification reported the presence of cervical HPV infection status, and the syndrome differentiation of TRADITIONAL Chinese medicine belongs to the wet-toxin type;
(4) Those who sign the informed consent.

Exclusion Criteria

(1) Liquid base thin layer cytological examination (TCT) of highly squamous intraepithelial lesions and infiltrating carcinoma, or histopathological examination of CINII and above high-grade lesions;
(2) Vaginal infections during the week prior to enrollment;
(3) Those who were using other drugs to treat HPV infection or immunosuppressive drugs in the first three months before inclusion;
(4) Women during pregnancy and lactation;
(5) people who have mental diseases or diseases of important organs or metabolic diseases of the body;
(6) Persons with infectious diseases, such as tuberculosis, hepatitis B, or venereal diseases;
(7) For bad life habits or recent exposure to toxic substances, such as drugs, X-rays;
(8) Therefore, other clinical trial investigators are being accepted.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HPV negative rate;

Secondary Outcome Measures

Name	Time	Method
TCM syndrome score;HPV recurrence rate;Gene sequencing of vaginal microecological environment;