Efficacy of White Kidney Bean Extract to Prevent Kidney Injury in Obese Population: A Randomized Controlled Trial

Not Applicable

Completed

• Conditions: Early stage of obesity- White kidney bean extract; Chronic kidney disease; related kidney disease; Obesity related nephropathy; Obesity

• Registration Number: TCTR20140323001
• Lead Sponsor: Pharmachem Laboratories, Inc.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-01-14
• Study Start: 2014-03-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

Non diabetic Thai healthy obese subjects
Body mass index 25 to 33 kg m2
Normal baseline serum creatinine
Normal complete blood count and liver function test

Exclusion Criteria

Uncontrolled obesity related co morbidities
Using of weight reduction agents within 4 weeks prior to study
History of bariatric surgery
Pregnancy and breast feeding female
Other active glomerular diseases
Active malignancy
History of bean allergy or G6PD deficiency
Drug abuse or alcohol drinking or smoking

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rinary Cystatin C-creatinine ratio (UCCR) After randomization (day 0) and at 12 weeks (complete the study) 10 mL first morning urine is measured for UCCR

Secondary Outcome Measures

Name	Time	Method
rinary albumin-creatinine ratio (UACR) After randomization (day 0) and at 12 weeks (complete the study) 10 mL first morning urine is measured for UACR,High sensitivity C-reactive protein (hs-CRP) After randomization (day 0) and at 12 weeks (complete the study) Blood measurement,Fasting plasma glucose After randomization (day 0) and at 12 weeks (complete the study) Blood measurement,Lipid profiles (total cholesterol, low density lipoprotein, high density lipoprotein, triglyceride) After randomization (day 0) and at 12 weeks (complete the study) Blood measurement