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Clinical Trials/CTRI/2024/12/077581
CTRI/2024/12/077581
Not yet recruiting
Phase 2/3

A Randomized Open Labelled Comparative Controlled Clinical Study to evaluate the efficacy of Dashmoola Avaleha and Shirish Avaleha in the Management of Vataja Pratishyaya (Allergic Rhinitis) in Children

Institute for Ayurved Studies and Research1 site in 1 country60 target enrollmentStarted: December 14, 2024Last updated:

Overview

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Institute for Ayurved Studies and Research
Enrollment
60
Locations
1
Primary Endpoint
Primary outcomes-

Overview

Brief Summary

Allergic Rhinitis (AR) is an inflammation of the nasal mucosa caused by an abnormal reactivity to an aeroallergen.Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, under diagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Allergic Rhinitis is an immunoglobulin E-mediated immunologic response of nasal mucosa to airborne allergens .Many treatment modalities are explained in Allopathic science like corticosteroids, anti-Allergic drugs, inhalers, antihistamines etc. but none of them are totally effective in curing the disease as well as preventing its recurrence, more over they have their own side effects like Rhinitis.So,this clinical trail has been designed to assess the efficacy of Dashmoola avaleha and shirish avaleha for oral administration in the management of Vataj pratishaya in children of age 6 year to 14 year is selected from O.P.D. of Kaumarbhritya Department of Institute for Ayurved Studies and Research.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
6.00 Year(s) to 14.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • 1 Signs and Symptoms of Vataja Pratishyaya (as per Ayurvedic classics) and Allergic Rhinitis (as per Allopathic science).
  • 2 Parents of children willing to participate in the study 3 Age group: Between 6 to 14 years, irrespective of sex, religion, or socioeconomic status 4 SFAR score greater than 7.

Exclusion Criteria

  • 1 Patients with a history of bronchial asthma, tuberculosis, pleural effusion, emphysema, lung abscess, bronchiectasis, pneumonia, or pleurisy 2 Patients below 6 years of age or above 14 years of age 3 Patients presenting with complications of allergic rhinitis such as nasal polyps, tumor of the nose, or deviated nasal septum (DNS) 4 Patients with a history of nasal surgery.

Outcomes

Primary Outcomes

Primary outcomes-

Time Frame: 14 days

I. It will be accessed on the basis of statistical analysis applied on subjective parameters after

Time Frame: 14 days

completion of trial.

Time Frame: 14 days

Secondary Outcomes

  • 1. Literary data related to Vataja Pratishyaya (Allergic rhinitis) will be compiled from different(texts of Ayurveda and modern part.)

Investigators

Sponsor
Institute for Ayurved Studies and Research
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Shruti Mehta

Institute for Ayurved Studies and Research

Study Sites (1)

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