eurofeedback with Gait imagery for PD

Phase 1

Recruiting

• Conditions: Parkinson Disease; Parkinson's disease, gait impairment, Freezing of G ait; D010300

• Registration Number: JPRN-jRCTs062220027
• Lead Sponsor: Mihara Masahito

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-08
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1) patients who had written informed consent
2) age older than 39 year old
3) PD patients with diagnosis of clinically probable or clinically established PD in MDS criteria
4) Patients with Hoehn-Yahr stage 2 to 4
5) Patients who can walk 10 m safely with or without aid
6) Patients whose anti-Parkinsonian drug is not changed for at least 2 months at the time of registration
7) Patients who can understand the verbal order and perform task

Exclusion Criteria

1) moderate to severe dmentia with MMSE score< 22
2) Patients with cortical lesion covering media premotor area including the supplementary motor area
3) Patients with history of symptomatic stroke or Epilepsy
4) patients with severe Anterior Cerebral Artery stenosis (>90%)
5) Patients wiht history of neurosurgical operation including Deep brain stimulation and trans-arterialaneurysm coil embolization)
6) Patients unstable in vital signs
7) Patients with corrected binocular visual acuity less than 1/20
8) Patients with scalp lesion which needed treatment
9) Women with Pregnancy, lactating, or suspected pregnancy
10) Patients who is unable to perform brain MRI scannning
11) Patients with past or current history of clinically established psychological illness (needs wnti-psychotic drugs).
12) Patients have experienced experimental brain stimulation intervention (including repetitive trans
cranial magnetic stimuration or transcranial direct/alternative current stimulation) within 6 months prior to the enrollment.
13) Patients with severe, unpredicable wearing-off which disturb stable evaluation in each visit
14) Patients with muscloskeltal complication which affect gait performance
15) Patients assumed to be inadequate fore enrollment by their attending physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified