Better control and treatment of Atopic Dermatitis disease by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies

Recruiting

• Conditions: eczema; topic dermatitis; 10014982

• Registration Number: NL-OMON51252
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1. Age >= 18 years at time of study entry
2. Written Informed Consent.
3. Diagnosis of chronic atopic dermatitis for at least 1 year prior to
enrollment
4. Use of licensed targeted immuno therapy within routine care

Exclusion Criteria

1. Experiencing or history of other concomitant skin condition that would
interfere with evaluations of the effect of medication on atopic dermatitis.
2. Patients with a tendency to develop hypertrophic scars

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Molecular stratification tools and *hard* molecular endpoints for disease<br /><br>control on the<br /><br>individual patient level.<br /><br>Aanalysis of tissue-derived signatures with *circulating signatures* detectable<br /><br>in liquid biopsies (bood and tissue liquids), employing state-of-the-art<br /><br>profiling technologies corresponding to multi-Omics datasets.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>